Crowley's An Introduction to Human Disease: Pathology and Pathophysiology Correlations

Crowley's An Introduction to Human Disease: Pathology and Pathophysiology Correlations, Twelfth Edition provides readers with a clear, well-illustrated explanation of the structural and functional changes associated with disease, the clinical manifestations of disease, and how to determine treatment. It reflects current information on the pathogenesis of infectious diseases and how changes in the genome are expressed as disease.

The first chapters of the text discuss general concepts and diseases affecting the body as a whole. Later chapters consider the various organ systems and their diseases. The Twelfth Edition has been significantly reorganized and streamlined to improve the flow of information and the reader experience. New content, updated data, and new illustrations and figures have been included throughout.

Key Updates:

• Chapter on Pregnancy and Fertility (15) extensively updated with new information on diseases and pathologies associated with pregnancy, discussion of maternal mortality rates in the U.S., and added information on both female and male infertility.
• Chapter on Congenital and Developmental Diseases (16) thoroughly revised to include updated discussion of teratogen thalidomide and key environmental factors affecting pregnancy.
• Streamlined structure: Chapters have been reorganized for a more intuitive progression of topics.
  • Coverage of the female and male reproductive systems has been consolidated into one chapter (18), with updated discussion of sexually transmitted diseases.
  • Pathology of both red and white cells consolidated into one chapter. (Ch. 11)
• Updated figures, tables, and end-of-chapter reading suggestions that support deeper learning.
• A wealth of new content, including:
  • Added information on epigenetics and their impacts on gene expression and new content on mitochondria diseases in humans (Ch.3)
  • Added information about cytokines and their functions (Ch.5)
  • New information on importance of vaccines in preventing transmission of infectious diseases (Ch. 7)
  • Added information on current outbreaks of avian flu (H5N1) and measles (Ch. 7)