AHFS Drug Information®

An Evidence-based Foundation for Safe and Effective Drug Therapy

AHFS Drug Information®
2022nd Ed.
2022 © American Society of Health-System Pharmacists®
American Society of Health-System Pharmacists
ISBN-10: 1-58528-684-2
Pharmacy/Pharmacology, Drug Information, Neurology, Ophthalmology, Point of Care, Public Health


AHFS Drug Information® 2022 contains the most dependable drug information available—all in one place. It is the most comprehensive evidence-based source of drug information complete with therapeutic guidelines and off-label uses.

With expanded and revised content supported by more than 97,000 references and incorporating the advice of numerous subject matter experts, AHFS DI helps you protect your patients and your practice.

Updates in the new edition:

  • • The latest information on COVID-19 vaccines and COVID-19 monoclonal antibodies available under FDA Emergency Use Authorizations (EUAs), including clinical considerations from the US Centers for Disease Control and Prevention (CDC), and National Institutes of Health (NIH)
  • • Information on patient selection and appropriate use of corticosteroids in the management of COVID-19 based on recent guidelines from NIH and the World Health Organization (WHO)
  • • Contemporary issues such as anticoagulant reversal strategies and use of direct oral anticoagulants versus warfarin for treatment of venous thromboembolism or atrial fibrillation
  • • Current best practices such as reversal of neuromuscular blocking agents for prevention of postoperative residual neuromuscular blockade
  • • Newly published information on breakthrough oncology drugs approved as part of the FDA’s accelerated approval program
  • • Expanded content on off-label uses, real-world data, and long-term clinical data
  • • Updated information on pharmacogenomic considerations based on recommendations from the Clinical Pharmacogenetics Implementation Consortium (CPIC)
  • • Addition of 51 new molecular entities (NMEs) or new therapeutic biological products approved since January 2021

This title updates: Monthly

Doody's Reviews

Doody's Core Titles (DCT)
Essential Purchase Title (EPT)
Specialty Score: 2.8 Health Sciences - Pharmacy
Go to Doody's Review page

Quotes, Reviews or Testimonials

"This book succeeds in offering an updated drug compendium of evidence-based drug monographs, meeting the needs of today's healthcare professionals. The reference continues to be trustworthy, relying on the most prestigious and knowledgeable drug experts in the medical field. Current topics are incorporated, such as breakthrough oncology drugs, pharmacogenomics, off-label drug uses, and opioid use disorder. It is a worthy addition to the personal library of physicians, pharmacists, nurse practitioners, and other prescribers."

-- Melissa Potts, BS, PharmD (Temple University School of Pharmacy) Doody's Review - previous edition

"This reference is widely used and trusted for its established record in refuting unfounded efficacy claims, its rigorous science-based editorial process, and its independence from the influence of pharmaceutical manufacturers."

-- Jennifer Colon, PharmD, MS, MBA (Temple University School of Pharmacy) - previous edition

"You cannot be a pharmacist without this book. For clinical pharmacists especially it is the standard..."

-- Miriam Klein, Pharm.D. R.Ph. (Woodhull Medical Center) - previous edition

“AHFS Drug Information is by far the most comprehensive and informative drug reference that I use. It offers much more in-depth information and post-marketing [after FDA approval] analysis on drugs.”

-- Jay S. Cohen, M.D., Associate Professor of Family and Preventive Medicine, University of California at San Diego Medical School - previous edition

“There is more in-depth information in AHFS DI, particularly pharmacology and kinetics. At times I especially need the unlabeled uses in AHFS Drug Information to answer questions. Other references don't include as many off-label uses.”

-- Paul Matuschka, Pharm.D., VA Medical Center, Louisville, KY - previous ed


This reference can be used by any healthcare professional utilizing or prescribing medications in their practice, including physicians, pharmacists, physician assistants, and nurse practitioners. The book is so nicely organized and easily referenced that it can also be used by students in the medical, pharmacy, and nursing fields as well. The drug monographs are prepared by a professional editorial and analytical staff, who critically evaluate published evidence on the drug. The monographs incorporate the advice of leading experts in the specific field under consideration, including those from major research and clinical institutions as well as public bodies such as the National Institutes of Health (NIH) and US Centers for Disease Control and Prevention (CDC) and professional associations with therapeutic authority. It is this process that makes the drug monographs evidence-based, authoritative, and unbiased.

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